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The mechanisms by which Grb2 regulates endocytosis of RTKs is not fully understood, and we can hypothesize that HD-PTP and Grb2 work together, probably with other proteins as well, to assemble and/or coordinate the assembly of endosome-associated protein complexes essential for vesicle biogenesis and protein sorting.
Keil, M. et al. Oxa1-ribosome complexes coordinate the assembly of cytochrome C oxidase in mitochondria.
Our finding that supramolecular interactions between the relatively small BTAs are sufficient to coordinate the assembly of protein complexes via DNA hybridization is quite remarkable.
During wound repair within epithelial monolayers in vitro, cells coordinate the assembly of branched and bundled actin networks to regulate the total mechanical work produced by collective cell motion.
Here, we review advances in our understanding of how these mechanisms act to shape structure and function at the single cell level, to coordinate the assembly of cell populations, and to define their specific circuitry.
More recently, betaArrestins have been shown to act as molecular scaffolds that coordinate the assembly of certain MAP kinase complexes that lead to the stimulation of either ERK1/2 or JNK3.
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This group managed the general space assignments for each sub-system and coordinated the assembly and planning for the detector.
The man in charge of coordinating the assembly of the reactor is Ken Blackler.
Thus, it is likely that Mcm2-7 coordinathe the assembly of other chromatin-associated proteins that play important roles in the cell-division cycle.
In S. cerevisiae origins the ACS is bound by the Origin Recognition Complex (ORC) which coordinates the assembly of the pre-replication complex (pre-RC) and the subsequent initiation of DNA synthesis [ 3, 13].
Despite reconstituting and visualizing ESCRT-III assembly with the resolution of TEM, it was unclear how Snf7 is conformationally activated, and how this activation coordinates the assembly of Snf7 polymers on membranes.
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