Ackman, J. B., Burbridge, T. J. & Crair, M. C. Retinal waves coordinate patterned activity throughout the developing visual system.
We observed the regionalized identity of cells along the anterior posterior axis of the emergent gut tube, reflecting their embryonic or extra-embryonic origin, and their coordinate patterning into organ-specific territories.
Both molecular biologists and clinical researchers could focus attention on the relatively small number of genes identified here as having coordinate patterns that arise from both the experimental system and the human disease system.
These stereotyped waves of retinal spikes have recently been shown to coordinate patterned activity across multiple visual areas [ 4], where they are proposed to mediate the sculpting and refinement of retinotopic and eye-specific maps [ 3, 5].
Here, we demonstrate that Sdf-1γ is a nuclear protein in the mouse heart, where it is expressed in a temporally coordinated pattern during development and at high levels postnatally and in adults.
Among its home furnishings were a wide range of fabrics; matching wallpaper and borders; ceramic tiles in coordinating patterns; pillows; sheets; and ornate baskets.
It was not pounding drums and clanking metal that produced the loudest sounds, but the whistles blown by the players in complex, coordinated patterns.
The handbags and accessories are decorated with stripes, plaids, denims and corduroys, sometimes from recycled curtains or slipcovers, with coordinating patterned linings.
Combining signature-based predictions across several pathways identifies coordinated patterns of pathway deregulation that distinguish between specific cancers and tumour subtypes.
