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In contrast to the majority of the molecules in the system, they possess similarly high and coordinate levels of differential co-expression compared to the abundant DE genes.
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A coordinate level is added to incorporate the pump control into the valve control.
For each group a graph O = (V, E) with vertices V and edges E is constructed, which represents the species-internal overlap of CNBs on the genomic coordinate level.
Third, impact of chemicals on ADME pathways are subject to complex feed-back and feed-forward loops at the nuclear receptor level, coordinating expression levels of both metabolic and transporter proteins with their requirement to handle fluctuating chemical levels [7], [12], [13], [14].
This article develops the Synchronous Matching Adaptive Resonance Theory (SMART) neural model to explain how the brain may coordinate multiple levels of thalamocortical and corticocortical processing to rapidly learn, and stably remember, important information about a changing world.
Given the generally large number of microRNA targets [10] it is natural to assume that many microRNAs regulate not only a single important pathway protein, but rather coordinate protein levels on a pathway-wide scale.
We now show that ectopic expression of Cyclin D/Cdk4 in the larval fat body is sufficient to drive mitochondrial abundance in a Delg-dependent manner (Fig. 8B), suggesting a mechanism where Cyclin D/Cdk4 coordinate growth levels and mitochondrial mass.
The NHS Connecting for Health system is an attempt by the UK government to coordinate all levels of care (primary, secondary, tertiary and community) using electronic health records, begun in 2002.
The National Institutes of Health have financed 17 Centers for AIDS Research, or C.F.A.R.'s, to coordinate high-level research into the disease.
Instead, these latter groups coordinate enterprise-level bargaining, especially for the annual "spring offensive" (shuntō).
Among 70 cytobands that showed coordinate mRNA level changes in AE, 20 were previously linked or associated to AE by genetic studies (28% overlap), whereas only 2 cytobands (3% overlap) were expected by chance alone (P<10−8, hypergeometric distribution).
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