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Although we were broadly able to affirm the conclusion of coordinate expression, there were clearly a number of tumours that expressed strongly one or other gene (Table 1).
An organism ultimately reflects the coordinate expression of its genome.
How cells coordinate expression of genes throughout the disc is an important but as yet poorly understood process.
Profiling transcriptomes as well as examining the coordinate expression of many genes in diverse pathobiologic pathways is now possible with techniques such as gene array analysis.
SF-1 binds to shared promoter elements upstream of the steroid hydroxylases to mediate their coordinate expression in steroidogenic cells.
However, the molecular mechanisms that coordinate expression of these genes and modulate their activities in response to biological stimuli are less well understood.
In mouse embryos, SF-1 expression in the urogenital ridge and brain either preceded or coincided with Dax-1 expression, with coordinate expression thereafter in the adrenal cortex, testis, ovary, hypothalamus, and anterior pituitary.
Genes with coordinate expression patterns during conjugation are candidates for participating in the same developmental process.
Interestingly, coordinate expression of all these factors promotes the expression of HB9, the common marker of motoneurons.
We also demonstrate that MITF expression is important for the coordinate expression of miR-211, and TRPM1.
Antigen induced IFN γ has been reported to correlate with TST diameter [38], but the coordinate expression of CF induced IL-10 was surprising.
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