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Embryonic organizers are signaling centers that coordinate developmental events within an embryo.
The abnormalities in segmentation are presumably due to the inability of the embryo to compensate for temperature-induced differences in rate of development and to coordinate developmental timing in the anterior and posterior halves.
Thus, while providing essentially the same activity, the unique (but potentially partially overlapping) transcriptional codes of N-Myc and c-Myc may have evolved to facilitate and coordinate developmental transitions that incorporate, and presumably require, a transient exit from the cell cycle.
PCA and K-means clustering of AAT transcript data revealed coordinate developmental stages in flag leaves, glumes and grains.
One of the best studied signaling pathways that coordinate developmental decisions is the Notch pathway [ 1- 3].
This clock allows organisms to anticipate predicted daily changes in the environment and to coordinate developmental and metabolic processes with environmental cues, such as light and temperature, that cycle with the rotation of the earth [ 1- 5].
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This review focuses on these conserved mechanisms and highlights recent studies that explore how Drosophila coordinates developmental growth with environmental conditions.
Hence subtle differences in the glycan structure of AGPs may function as markers used in coordinating developmental processes in plants.
These timed programs involve signaling systems that respond to nutritional and environmental cues to direct coordinated developmental responses throughout the animal, such as transitions in morphology.
For example, HoxA10 can simultaneously affect both cell proliferation and differentiation during the development of hematopoiesis, resulting in precise and highly coordinated developmental changes of blood cells.
The developmental signaling centers for the maxillary and mandibular arches are independent, with only a few factors to help coordinate their developmental growth [ 8].
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