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The above data demonstrate that residue Asp149 is mainly involved in the specificity in the recognition of RolR with resorcinol ligand, while the residues Arg148, Asp94 and Arg145 are cooperatively involved in determination of the binding affinity of RolR to resorcinol.
Thus, DBC1 and SIRT1 might be cooperatively involved in gastric tumorigenesis via histone acetylation.
> -wrap-foot> We show that the method successfully identifies the residues cooperatively involved in MDR, as well as the mutational patterns arising from different drug treatments.
Therefore, there is a possibility that NGF and HO1 are cooperatively involved in the tumorigenesis via their roles in cellular adaptation to stress and resistance to apoptosis.
Our results revealed that distinct differentially expressed proteins in seed embryo and endosperm are cooperatively involved in seed germination, which provides new insights into the proteomic mechanisms of wheat seed germination.
In Xenopus, BMP2/4 regulate Wnt-8 expression and cooperatively involved in the mesoderm patterning, whereas BMP2 downregulates Wnt7a and β-catenin in chicken embryonic mesenchymal cells in a p38-dependent manner, leading to enhanced chondrogenesis.
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Still, their participation in the DRC suggests that the resistance mechanism cooperatively involves several residues.
The precise role, if any, of such filaments is unknown, although NS1 'tubules' made up of multiple filaments were proposed to be involved in cooperatively binding dsRNA [27].
Mr. Jones "has more than exceeded my expectations," said Kenneth Thorn, chairman of the theater's board, adding that the new executive director has reinvigorated board members to become involved while working cooperatively with the artistic side of the house.
In addition, we found that one miRNA in the miRNA association network could be involved in many cooperatively regulating miRNAs in a condition-specific and combinatorial manner.
In the natural world, microorganisms interact with their environment and with each other, often competing for space, light and nutrients, but sometimes they act cooperatively, which benefits all parties involved.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com