Sentence examples for cooperative prospective from inspiring English sources

Combined multimodality treatment, utilising chemotherapy and radiotherapy, without surgical resection is advocated but a cooperative prospective study would lead to further improvement in treatment outcomes.

Therefore, we planned a multicenter, cooperative, prospective, randomized phase II study to compare daily and alternate-day S-1 administration as postoperative adjuvant therapy for CRC.

These changes in management illustrate the need for large cooperative prospective studies in PPL, which will better define any benefit of resection, as well as the role of therapies such as radiotherapy and rituximab.

Given the very poor prognosis of the medically inoperable patient population, these alternatives to surgery, particularly SABR, are starting to be considered appropriate first-line therapy in properly selected patients, and prospective cooperative group trials to evaluate and optimize RFA and SABR in specific patient subsets are being conducted.

These exciting early findings are now being tested in a large prospective cooperative group trial.

The potential to use this information must be tested in larger, prospective, cooperative trials.

At least four prospective, cooperative group, randomised multicentre trials have demonstrated that a combination of low-dose IFN-α with other agents does not improve outcome (Table 4).

Before any single or panel of markers can be introduced as a reliable parameter for the evaluation of clinically relevant MD or MRD, their clinical significance must be demonstrated in large prospective cooperative multi-centre studies, performed according to SOPs.

Surgical complications associated with sentinel lymph node biopsy: results from a prospective international cooperative group trial.

METHODS: In this phase II, prospective, multicenter, cooperative group trial, high-risk patients had one or more of the following risk factors: forced expiratory volume in 1 second less than 40%, carbon monoxide diffusing capacity in lung less than 50%, and maximum oxygen consumption less than 45 mm Hg.

The European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups developed a prospective randomized phase III trial in patients with AML aged between 46 and 60 years, to test two different dosages of cytarabine in post-remission treatment.