Sentence examples for cooperative induction from inspiring English sources

Given the potent mitogenic activity of combined HH/GLI and EGFR, e.g. in neural stem cells (Palma et al, 2005; Palma & Ruiz i Altaba, 2004), we first tested whether HH-EGFR cooperation promotes oncogenic transformation by cooperative induction of cell cycle regulators.

Stromal cell-derived factor-1 alpha and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: a potential mechanism for cooperative induction of chemotaxis.

This was accompanied by cooperative induction of DNA damage by the drug combinations, as reflected by the induction of γH2AX.

Therefore, the cooperative nuc-1 remodeling we observed by indirect end-labeling following a prostratin+VPA cotreatment was not due to a cooperative induction of histone H4 acetylation.

Our mechanistic studies revealed that cooperative induction of DNA damage by the two agents and induction of Bim by VPA underlay the observed synergistic antileukemic activities of this drug combination.

Enforced expression of ectopic c-FLIP, but not survivin, abolished the cooperative induction of apoptosis by the combination of LBH589 and TRAIL, indicating that c-FLIP downregulation plays a critical role in LBH589 sensitization of pancreatic cancer cells to TRAIL.

Accumulating evidences suggest that STAT3 also associates with other transcription factors to form enhanceosome complexes in the promoter regions of target genes and controls cooperative gene induction [23], [24], [25].

While previous work has demonstrated an important role for SDF-1α in mediating colon cancer cell migration and metastasis and VEGF has been previous linked to cell migration, to our knowledge this is the first observation that these two chemokines may be cooperative in the induction of cancer cell migration [35], [40].

In this study, we found that CnB and IFN- γ had a significant cooperative effect on the induction of these two critical transcription factors.

When poly(I C) is combined to the IAP inhibitor RMT 5265, a cooperative effect in apoptosis induction and/or inhibition of clonogenic growth is obtained in a large fraction of carcinoma and melanoma cell lines.

When poly(I C) was combined with the IAP inhibitor RMT 5265, we observed a cooperative effect in apoptosis induction and/or inhibition of clonogenic growth in a wide range of cancer cells.