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For example, the vertebrate organizer is localized by interactions between Wnt and TGF-β signalling pathways [29] [31], with TCF and SMAD, as respective effectors of these pathways, cooperating to regulate gene expression [31].
These results are in agreement with ATM and mutant p53 cooperating to regulate NF-κB signaling that results in IL-8 expression.
Terminal selectors work combinatorially, with multiple transcription factors cooperating to regulate sets of terminal effector genes that are necessary for each neuron's mature identity, such as neurotransmitters, channels, and synaptic adhesion molecules (Hobert, 2011).
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These data suggest that both FoxO3 and Smad2/3 are activated and cooperate to regulate TGF-β-induced Bim up-regulation.
Numerous studies have begun to explore how two or multiple TFs cooperate to regulate genes and what the degree of the cooperativity of these TFs is.
a5 and av integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo.
This review discusses how the various endogenous SFK inhibitors cooperate to regulate SFKs in normal cells.
Canel, M. et al. Nuclear FAK and Runx1 cooperate to regulate IGFBP3, cell-cycle progression, and tumor growth.
Chen, H. et al. MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation.
Lau, K.S. et al. Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.
Rodal, A. A., Motola-Barnes, R. N. & Littleton, J. T. Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth.
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