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First, there have to be large and clear gaps between cooperating and not cooperating to overcome the tendency of countries to solve their problems unilaterally.
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Minn, A. J., Boise, L. H. & Thompson, C. B. Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage.
The research published Sept. 15 in Science also demonstrates why it's advantageous for cells to cooperate to overcome their meager individual decision-making abilities by forming multicellular organisms.
In this report, we examined the mechanisms via which memory-like CD8+ and CD4+ T cells cooperate to overcome cross-tolerance and induce self-reactivity under lymphopenic conditions.
Thus, BAFF and T cells cooperate to overcome tolerance in NZB dTg mice in the setting of abnormal B cell function.
TNFα and IFN-γ cooperate to overcome TRAIL resistance at least partially through enhancing caspase 8 activation and repressing Bcl-xL expression.
In breast cancer cells, Met and Src were found to cooperate to overcome gefitinib-induced EGFR inhibition [ 41].
They gave quite elaborate reasons for cooperating: cooperating to establish reputation; cooperating because the other person might cooperate; whatever.
They need to cooperate with conspecifics to overcome predators or even the dominance of a pair of territorial breeders (Marzluff & Heinrich 1991).
Our data illustrated the ability of allosteric inhibitors such as GNF-2 to cooperate with AKIs to overcome T315I mutation by Bcr-Abl-independent mechanisms, providing a possibility of enhancing AKIs efficacy and overcoming resistance in Ph+ leukemia cells.
In this paper, we propose EFFORT, a new host network cooperated detection framework attempting to overcome shortcomings of both approaches while still keeping both advantages, i.e., effectiveness and efficiency.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com