Your English writing platform
Discover LudwigExact(55)
These data suggest that both FoxO3 and Smad2/3 are activated and cooperate to regulate TGF-β-induced Bim up-regulation.
Numerous studies have begun to explore how two or multiple TFs cooperate to regulate genes and what the degree of the cooperativity of these TFs is.
This review discusses how the various endogenous SFK inhibitors cooperate to regulate SFKs in normal cells.
To assess whether FoxO3 and Smad2/3 could be activated simultaneously and cooperate to regulate target gene transcription, double immunostaining assays were performed.
However, Chen et al. confirmed that the reversible phosphorylation of FUNDC1 Ser13 and Tyr18 functionally cooperate to regulate FUNDC1-mediated mitophagy (Chen et al., 2014).
This binding strategy is likely representative of many activators that target multiple coactivators, as it allows great flexibility in combinations of activators that can cooperate to regulate genes with variable coactivator requirements.
Similar(5)
For example, the vertebrate organizer is localized by interactions between Wnt and TGF-β signalling pathways [29] [31], with TCF and SMAD, as respective effectors of these pathways, cooperating to regulate gene expression [31].
We thus speculated that Celf3 and SF1 cooperated to regulate certain nuclear processes in a cell type-specific manner, as observed in the Neuro2A cells.
These results are in agreement with ATM and mutant p53 cooperating to regulate NF-κB signaling that results in IL-8 expression.
Terminal selectors work combinatorially, with multiple transcription factors cooperating to regulate sets of terminal effector genes that are necessary for each neuron's mature identity, such as neurotransmitters, channels, and synaptic adhesion molecules (Hobert, 2011).
Nuclear FGFR1 cooperates to regulate FGF-2, ribosomal S6 kinase (RSK1) and CREB-binding protein, with RSK1 capable of further promoting nuclear localisation of FGFR1 (Dunham-Ems et al, 2006, 2009).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com