Sentence examples for cooperate in the regulation of from inspiring English sources

Additionally, many cis-elements co-localize in the long upstream sequences and cooperate in the regulation of gene transcription (Carrera and Treisman 2008).

The enrichment of E-boxes further indicates that the circadian clock and the light response are closely intertwined and cooperate in the regulation of many light induced genes.

Indeed, previous studies have reported that AP-1 and PU.1 can cooperate in the regulation of cellular genes in macrophages [48], such as for the adipose differentiation-related protein gene [51].

In triploblastic animals, Runx and CBFβ proteins are known to cooperate in the regulation of gene expression by binding DNA as heterodimers (see [ 51] and references therein).

It has been well established that DNA methylation and histone modifications cross-talk and cooperate in the regulation of gene transcription.

The EAF2−/−VHL+/− mouse model demonstrates that these two tumor suppressors cooperate in the regulation of angiogenesis and that loss of these genes contributes to the development of neoplasia in the liver and prostate.

Moreover, how these enzymes cooperate in the context of regulation of epithelial and endothelial barrier function needs further investigation.

The induction of TSLP by combination of TNF-α and Th2 cytokines but not by the individual cytokines suggests that NFκB and STATs cooperate in transcriptional regulation of the TSLP gene [ 17].

Given the previously described role of HSP27 in the proteasomal processing of GATA-1, HSP70, and HSP27 thus cooperate in the fine-tuning of terminal erythropoiesis through the regulation of GATA-1 content and activity.

Through protein interaction studies, Esrrb was found to bind to Oct4 and cooperate in transcriptional regulation of Nanog (van den Berg et al., 2008).

In addition, we found new transcriptional partners of Pax8, which functionally cooperate with Pax8 in the regulation of thyroid gene transcription.