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These interactions between the Wnt and PS-1 signaling pathways suggest that they may cooperate in the pathogenesis of some human neurodegenerative and neurodevelopmental diseases, possibly even playing a role in LND.
ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer's disease.
59– 64 Thus, as Capn4 also induced activation of the NF-κB pathway, it is possible that LMP1 and Capn4 may cooperate in the pathogenesis of NPC.
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I published work on ribosomal haploinsufficiency causing selective activation of p53 in human erythroid progenitor cells and on the effects of a microRNA cooperating in the pathogenesis of the 5q- syndrome.
The evidence for multiple cooperating events in the pathogenesis of the rheumatic ADs resembling those observed in multistep carcinogenesis has been noted [ 43].
Muto, T. et al. Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.
IMPACT: These findings provide the first demonstration that secondary genetic alterations can cooperate with loss of VHL to cause kidney tumour formation and implicate TP53 mutations in the pathogenesis of a subset of human ccRCC.
Type I interferon in the pathogenesis of lupus.
Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases.
Innate and adaptive immunity in the pathogenesis of atherosclerosis.
He is a Burroughs Wellcome Investigator in the pathogenesis of infectious disease.
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