Sentence examples for cooperate in the activation of from inspiring English sources

Besides the canonical Wnt signaling pathway, many players cooperate in the activation of β-catenin.

We conclude that p110 CUX1 and GLIS1 can cooperate in the activation of Wnt genes in human breast cancer cells.

Thus, WRKY18 and WRKY40 cooperate in the activation of the WRKY60 gene expression mostly likely through recognition of the W box sequence in the WRKY60 gene promoter.

Here we demonstrate that Meis1, Pbx1 and HoxA9 cooperate in the activation of Hif-1α (Hif-1α-pGL2 reporter) (Fig.  6d).

In addition, we also found that Wnt-induced GBM cell differentiation inhibits Notch signalling, and thus gain of Wnt and loss of Notch cooperate in the activation of a pro-neuronal differentiation program.

As SopE and Arf1 cooperate in the activation of the WRC, it is possible that Arf1 is recruited by Salmonella to promote this synergy with SopE for triggering membrane ruffling and invasion.

Oct4 has also been demonstrated to physically interact with Wdr5, a core member of the mammalian Trithorax complex, and cooperate in the transcriptional activation of self-renewal genes [ 36].

Co-expression experiments in MCF10A untransformed mammary epithelial cells demonstrated that CUX1 and GLIS1 cooperate in the autocrine activation of the Wnt/β-catenin pathway and in stimulating cell migration and invasion.

Since, in the present study, surface CD40 was detected on a fraction of neuroblasts from the individual tumours, CD40L-induced apoptosis of malignant cells and immune activation may cooperate in the elimination of CD40+ and CD40− neuroblasts, as already shown in a different neoplastic model (Dotti et al, 2002).

Thus, it is conceivable that additional viral and cellular proteins cooperate with K13 in the activation of the NF-κB pathway, inhibition of lytic replication and dysregulation of viral and cellular gene expression programs during KSHV tumorigenesis (Figure 8).

This indicates that SNTA1 and P66shc cooperate and function in the activation of the Rho GTPase Rac1.