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The two genes seem to "cooperate" in causing cancer, Dave said, suggesting gene therapy for diseases not involving gamma c--which itself may be oncogenic when inserted with a retrovirus--may be safer.
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Additionally, since K13 mRNA is expressed as part of a bi- or tricistronic message with vCyclin and/or LANA-1 [61], selection of K13-over-expressing clones may simultaneously select for clones with elevated vCyclin and/or LANA-1, which may cooperate with K13 in causing progressive dysregulation of viral and cellular gene expression programs during KSHV tumorigenesis (Figure 8).
The draftees' refusal to put on a uniform or cooperate in any way caused difficulties for both the government and the COs.
But not people willing and able to cooperate in a murderous cause.
The etiology of cholesteatoma is not yet completely understood, but various studies have revealed that a number of factors cooperate in a synergistic way to cause the forming of this nonneoplastic keratinizing lesion, which is characterized by enhanced proliferation of epithelial cells with aberrant morphologic characteristics [ 1, 5– 7].
Indeed, CD4+ and CD8+ T lymphocytes, platelets, monocytes have been shown to cooperate in the cerebral microvasculature, and this causes inflammation, endothelial cell damage, and hemorrhages [ 9, 20, 28- 30].
The aim of this paper is to analyze the motives that have caused industrial firms to cooperate in R&D.
The statement by the French transportation ministry said French and British experts would jointly monitor the inquiry into the causes of the crash and cooperate in proposing modifications by the Concorde's builders to prevent burst tires from causing fire.
The behaviourists, veterinarians, experienced breeders and kennel clubs must cooperate in the education of breeders and dog owners to prevent mental problems caused by the raising and management of dogs.
The Kremlin denied having any knowledge about the cause of Skripal's illness, and offered to cooperate in the investigation.
After declining to take up the recount cause, Clinton's campaign said last weekend that it would cooperate in the process.
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