However, mammalian cell lines have produced conflicting data regarding the ability of cooling to trigger ER stress and downstream events coordinated by the unfolded protein response (UPR) (Hofman et al., 2012, van der Harg et al., 2014).
Our results indicate that there was a decrease in the specialization degree of rodent faunas during the Pliocene due to the global cooling that triggered the onset of the glacial events of the Cenozoic (around 2.75 Ma).
These speciation events match very closely the estimates of the formation, in the late Miocene, of a major east-Antarctic ice sheet with its associated polar cooling, which triggered the aridification of mid-latitude continental regions and a shift in North Africa from forest to dry open woodlands and savannahs [ 4, 20, 108].
When ambient temperature drops, the flowers cool slightly, triggering a heat-producing "breath".
Three years after an earthquake and tsunami knocked out its cooling system and triggered a triple reactor meltdown, TEPCO is keen to show that progress is being made on decommissioning the plant.
Also making the top 20 are Smart Phone Exercise Apps, Worksite Health Promotion, Outcome measurements (set a goal and be accountable!) and Flexibility / Foam-Rolling which can be used for warming up, cooling down, trigger points or just a DIY deep tissue massage for cheap.
Certainly, a shift to a warming Niño this winter, following two successive years of cooling Niñas, could trigger a record high in the surface temperature of the eastern Pacific.
The combination of photodissociating and photoionizing radiation may enhance the formation of H2 in a thin shell ahead of an H ii region, which may trigger cooling and collapse in nearby halos (Haiman et al. 1996a; Ricotti et al. 2001; Kitayama et al. 2004; Ahn and Shapiro 2007; Susa and Umemura 2006; Susa 2007; Susa et al. 2009; Whalen et al. 2008a, 2010).
Since cold-shock can activate PERK (Hofman et al., 2012) and JUN (Fig. S1), both of which are components of the UPR, we postulated that cooling could trigger ER stress — the principal driver of UPR activity (Walter and Ron, 2011).
This strategy, called Cooler Trigger Model (CTM), involves dynamically controlling the switching frequency and the switch 'ON′ time of cooler compressor so that the heat extraction is in accordance with the heat generation.
