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As with the bird, the insect sequences show a rather convoluted assembly, with regions where two or three sequences align in parallel to the same region of the reference.
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The convoluted modular assembly of the TCR signalling machine controlled by sequential phosphorylation events and regulatory mechanisms provides the molecular framework for accurately and unfailingly executing these subtle tasks (Altan-Bonnet & Germain, 2005; Acuto et al, 2008).
Major obstacles to understanding cortical architecture include the diversity of cell types, their highly recurrent local and global connectivity, dynamic circuit operations, and a convoluted developmental assembly process rooted in the genome.
This interpretation has become even more convoluted following the observation that prolonged rapamycin treatment may inhibit AKT signalling by interfering with the assembly of the second mTOR complex, mTORC2 [ 21].
Remember "convoluted"?
The nomenclature is convoluted.
It's convoluted.
I know this is convoluted.
Are the rules convoluted?
"It's so convoluted".
These deals were really convoluted".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com