Such methods are used in other research fields, and the application to large-scale neuronal recording data will enable investigators to determine the variable properties that convincingly contribute to the variances in the observed neuronal measures.
While TRAIL up-regulation was convincingly shown to contribute to the selective HDACi-induced apoptosis of tumor cells, our results provide first evidence that up-regulated 4-1BBL might further contribute to the in vivo anticancer action of HDACi such as MS-275.
TNF was the first cytokine convincingly demonstrated to contribute to chronic inflammation in several autoimmune diseases, including rheumatoid arthritis (RA) and Crohn disease [ 4].
Science-based climate models have convincingly implicated anthropogenic forces as contributing to the increased extent and severity of droughts in the region.
But the end-of-cycle review convincingly demonstrates how UNICEF contributed to and added value to many of these responses," Mr. O'Malley said.
Furthermore, even if neutrophils and NK cells were convincingly demonstrated not to contribute to acetaminophen toxicity, this does not exclude a potential role of the innate immune system in hepatotoxicity induced by other drugs and compounds.
Recent studies have convincingly demonstrated that apoptosis also plays a pivotal role in numerous pathological processes, contributing to the adverse effects of various diseases and traumatic conditions.
Nonetheless, HGF/MET activation has been convincingly implicated in mesothelioma pathogenesis, with this ligand/receptor pair co-ordinately overexpressed (Tolnay et al, 1998) and apparently contributing to invasiveness and proliferation (Klominek et al, 1998; Harvey et al, 2000).
That study convincingly showed that B cells may contribute to the development of lupus in ways that are independent of autoantibodies.
Using orthotropic arterial transplantation, the authors convincingly demonstrate that circulating cells rarely contribute to plaque endothelium or regeneration of overlying endothelium after plaque disruption.
