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CBP has been considered for long time as the only interacting partner of CREB as it conveys activation of CREB to the basal transcription machinery [9].
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LPAR3, which was found to be the most likely mediator of the migratory effect of LPA in the oral cancer cells studied here, is known to couple to Gq and phospholipase C β (PLC-β) and can thus convey activation of PKC.
Reversible ubiquitinylation of key adaptors is required to convey the optimal activation of NF-κB.
Taken together, our data indicate that factor(s) retaining cytoprotective properties in IPC effluent are conveying cardioprotection via activation of Akt-dependent signaling that can be modulated at reperfusion after a lethal ischemic insult.
This can be explained both by the higher iSNR (cf. Tables 2 and 3) and the fact that the spectro-temporal activation of speech itself conveys information [43].
Indeed, activation of DRs also conveys alternative, non-apoptotic signaling pathways involved in cell survival, differentiation, or the control of inflammatory and immune responses.
This has led to the suggestion that l-deprenyl conveys its protective effects via the activation of antiapoptosis pathways within the cell, and that this neuroprotection is independent of MAO-B inhibition.
Activation of FUSCs may convey female specific gender-identifying information.
The activation of both regions activates the metaphorical link.
It is known from genetic analyses that perception of Gram-positive bacteria (such as S. aureus) crucially depends on the activation of TLR2 signalling, mainly conveyed through di-acetylated lipopeptides [ 48, 49].
Radiation-induced DNA damage elicits a signal transduction pathway that begins with sensor/activator proteins that lead to the activation of transducers that further convey the signal to multiple downstream effectors [ 66].
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