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Moreover, signaling cascades regulating EMT have been shown to convey stem cell phenotype to neoplastic cells which would account for their ability to metastasize and for their multidrug resistance 14.
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Fibronectin-coated pharmacologically active microcarriers (FN-PAM), are biodegradable and biocompatible polymeric microspheres that can convey mesenchymal stem cell (MSCs) and therapeutic proteins delivered in a prolonged manner.
We now know that mechanical forces at the cellular level guide stem cell differentiation, convey the health benefits of exercise, and underlie our ability to sense touch, sound, and pain.
Local mammary stem cells therefore accommodate the capacity not only to control the specific patterns of the branching ducts they produce, but also to control the ability to convey this dominion to their stem cell progeny (Smith GH, Boulanger C, Strickland P, Daniel C, manuscript submitted).
Our challenge was therefore to convey the key concepts of stem cell biology in a way that efficiently engaged the students, demonstrated the relevance of science to their lives, was fun for all involved and enabled all students to place science appropriately within their imagined futures.
The role of vehicles that convey molecular cues into the aged brain stem cell niche may provide means to treat diseased neural stem cells.
One of the major cellular mechanisms by which stem cells convey signals within their niche is via ligand-receptor interactions.
Stem Cell.
Cell Stem Cell.
Cell stem cell.
Cell stem Cell.
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