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"That helped," said Michael Collins, a 49-year-old inmate who sits a few feet from a dank corner converted into a group of metal toilets and open shower stalls.
In his front yard sits an old farmhouse he is having converted into a group therapy space.
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Fortunately, the ring-opened analogue 7 was fivefold more potent than our screening hit 4. The potentially unfavorable nitro group of 7 was subsequently converted into a trifluoromethyl group (in 8) without loss in potency.
One hydrogen atom from the benzene ring is converted into a methyl group (c).
As we walked toward the river that divides the city, the Nieuwe Maas, we passed a large brick church that had been converted into a mosque, groups of Turkish men playing cards, and, among the neighborhood stores, several "coffee shops" of the sort that do not sell coffee.
These two enzymes introduce a sialic acid on each N-glycan terminus, which is subsequently converted into an aldehyde group using NaIO4 under mild oxidation conditions.
The nitro group serves as a precursor for an amino group which can be converted into a reactive isothiocyanate group.
During electrolysis, the C-7 carbonyl group of 7K-LCA is converted into a 7β-hydroxy group on the cathode surface.
With the correct amount of aprotic solvent, the C-7 carbonyl group of 7K-LCA can be selectively converted into a 7β-hydroxy group on the cathode surface.
In this way, an alcohol, enol or sulfide is converted into a good leaving group for subsequent reaction with an acceptor alcohol.
The building has recently been converted into a theatre, and a group of young actors and dancers are rehearsing for a new play – a fusion of dance, drama and film – about Iraqi poet Mudaffer al-Nawab.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com