GI numbers were converted to Entrez Gene IDs using the gene2accession conversion file from NCBI.
A postal code conversion file (PCCF) [ 23] was obtained from Statistics Canada.
The mid-point for each FSA was obtained by using the postal code conversion file (Postal code conversion file January 1999 edition, produced by Statistics Canada) [ 9], obtained from the data library service of the University of Toronto, Toronto, Canada.
Additionally outputted from SEG-Map was a conversion file for genetic to physical positions on all estimated breakpoints.
Another input file is the Y-SNP conversion file containing all the essential data of the Y-SNPs for which mutation conversion is scientifically reported.
We identified Edmonton residents from the AH registry file using the community name variable from the Statistics Canada Postal Code 2008 Conversion file [ 14] (www.statcan.gc.ca).statcan.gc.ca
The SNP status file shows the state of all Y-SNPs which are given in the Y-SNP mutation conversion file.
Therefore, our BioPAX conversion file loads an INOH extension ontology to add our original properties to BioPAX class via OWL's import mechanism.
Each patient's DA of residence was identified based on their postal code and then linked to the Statistics Canada postal code conversion file (PCCF).
The Postal Code Conversion File, available from Statistics Canada, was used to link the six-character postal codes to the standard 2006 Census dissemination areas.
