Sentence examples for conversion of malate from inspiring English sources
The cellular NADPH pool is also sustained by PPP, through IDH1/2-mediated conversion of isocitrate to αKG, and by ME1-mediated conversion of malate to pyruvate [10].
Previously, numerous studies have elucidated the role of ME in NADPH supply via conversion of malate to pyruvate and proposed as rate-limiting factor for fatty acid biosynthesis (Hao et al. 2014; Li et al. 2013; Liu et al. 2013; Wynn et al. 1999).
NADP-ME (ME) catalyzes the conversion of malate to pyruvate.
Malate dehydrogenase catalyzes the NAD-dependent reversible conversion of malate into oxaloacetate [45].
The mqoB− mutant lacks the most potent enzyme for the conversion of malate to oxaloacetate.
The two latter FAD-dependent enzymes catalyze the conversion of malate to oxaloacetate whereby the electrons are donated to quinones of the electron transfer chain.
There was also an increase in the rate of fumarate conversion to malate, which accompanied the onset of cellular necrosis.
Owing to the low-malate signals observed, dynamic measurements of fumarate conversion to malate could not be performed in vivo.
Significantly up-regulated were: pyruvate kinase (EC 2.7.1.40) which is responsible for ATP production in glycolysis, and the conversion of pyruvate to malate via (S -Malate:NADP+ oxidoreductaS -Malate.1.1.38, 1.1.1.39, 1.1.1.40).
The subsequent conversion of OAA into malate in the green stages by cytosolic malate dehydrogenase (cMDH) is also well supported by the cMDH profile, by the active glycolysis and PEPC in this phase as continuous sources of NADH and OAA, respectively, and by the thermodynamics of the reaction itself.
Since high levels of malic acid are synthesized in berries until veraison, and both the concentration and absolute level rapidly decrease after veraison [ 3], it is not surprising that a cytoplasmic malate dehydrogenase (MDH; XM_002278672.2), which catalyses the reversible conversion of oxaloacetate to malate, was highly abundant at all stages.
