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We conclude that little behavioral improvement can be seen until AADC activity reaches a level that is no longer rate limiting for conversion of clinical doses of l-Dopa into dopamine or for trapping of the PET tracer FMT.
We introduce a Web-based, modular, distributed architecture, the Digital Electronic Guideline Library (DeGeL), which facilitates gradual conversion of clinical guidelines from text to a formal representation in chosen target guideline ontology.
Conversion of clinical parameters into integer values.
Electronic data captured at the point of care provides an efficient means for the conversion of clinical data to surveillance information.
Based on the study performed on conversion of clinical models between the openEHR archetype format and the COSMIC template format, a strategy to add archetype support in current generation EHR systems was formulated.
The strategy can be summarized by the following logical steps: 1. Study the bi-directional conversion of clinical content models between the archetype based format (both RM and AM) and any target EHR content format.
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A unique set of blood analytes is required to successfully predict the conversion of pre-clinical AD participants and also to differentiate controls from MCI progressors and those who do not progress to further cognitive decline.
There remains a strong case for intervention to prevent conversion of prediabetes to clinical type 2 diabetes, which is recognised in current management guidelines.
Preventing or reversing the progressive insulin resistance and/or β-cell dysfunction associated with dysglycaemia holds the key to preventing or delaying the conversion of prediabetes to clinical type 2 diabetes.
H-MRS examination was used for identifying MCI, distinguishing between MCI and normal controls [ 44, 45] and result of examination was evaluated as a predictor of clinical conversion of MCI to AD dementia based on clinical followup [ 46, 47].
In the largest prospective cohort, PIB-positivity was associated with declining memory and visuospatial performance [ 31], and was the strongest predictor of functional decline (conversion from clinical dementia rating of 0 to 0.5 or 1) [ 32].
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