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Exact(1)
Because the presence of an enzyme accelerates the rate of conversion of a compound to a product, it accelerates the approach to equilibrium; it does not, however, influence the equilibrium point attained.
Similar(59)
Consideration has been given to possible changes which could be made to the liver activation system (the S-9 mix) currently used in in vitro carcinogenicity assays, and a diagram is presented of the metabolic conversions of a compound which might lead to mutation or tumour formation.
The diff-only feature vector is expected to capture substructure changes around the reaction center in the conversion of a chemical compound to another compound.
In addition, the diff-common feature vector is designed to capture conserved substructures kept in the conversion of a chemical compound to another compound.
In addition, the diff-common feature vector is designed to capture core substructures kept in the conversion of a chemical compound to another compound.
The diff-common feature vector is expected to additionally capture core substructures kept in the conversion of a chemical compound to another compound.
Thus, the both feature vectors are designed to capture substructure changes around the reaction center in the conversion of a chemical compound to another compound.
Both feature vectors can handle reversible reactions, and they are designed to capture substructure changes around the reaction center in the conversion of a chemical compound to another compound.
In most instances, the mode of action is through the cellular conversion of a precursor compound to an active triphosphorylated form that might inhibit cellular or viral DNA synthesis, interfere with nucleotide metabolism, or become incorporated as a toxic lesion into the DNA of rapidly dividing tumor cells.
Absorption measurements provided a facile method to follow the conversion of compounds A and D into their metabolite product B. Altogether, the experimental data demonstrate that the replacement of the NHCHO substituent of compound A with a hydrophilic NHCH(CH2OH 2 chain preserves the intact imide function that is known to be essential for topoisomerase I inhibition and cytotoxicity.
Scheme 2 Conversion of compound 2 into compound 4. Unlike compound 2, compound 3 forms crystals 5 (Scheme 3).
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