Sentence examples for conversion in vitro from inspiring English sources
Moisan, Cowan and colleagues perform a small-molecule screen to identify compounds that promote white-to-brown adipocyte conversion in vitro.
Antibodies directed against PrPc have been shown to inhibit PrPc to PrPSc conversion in vitro and protect in vivo from disease.
Normal brain homogenate (NBH), the substrate for prion conversion in vitro, was prepared from tg5037 mice in a room that had not previously been used for prion research.
Beside those classical protein denaturants other compounds have been identified (e.g. glycosaminclycans and oligonucleotides) to promote PrP conversion in vitro but their structural influence on PrP remains unknown [23], [24].
Normal brain homogenate (NBH), the substrate for prion conversion in vitro, was prepared in a room that had not previously been used for prion research as follows: naïve tg1536 mice were euthanized intraperitoneally with 15 mg of sodium pentobarbital and perfused with 25 ml of 5 mM EDTA in PBS via intracardiac catheterization.
In a previous recent work, we show that the mutagenic activity of the error-prone DNA polymerase Pol IV and the MRS loss-of-function, major factors involved in the inducible and stable hypermutability of the cell respectively, are key determinants targeting mucA for mucoid conversion in vitro [21].
Let ϕ be a conversion factor between IC50 t)in vitro and IC50 t)in vivo and it can be estimated from data.
Our results indicate the in vitro conversion assay used in our study does mimic the species barrier of mice to the TSE agents that we tested.
The chitosan/Fe3O4@IL microcapsules showed high MW conversion efficiency in vitro MW heating experiment.
Conversion of in vitro MPCs into clinically useful data requires use of pharmacokinetic and pharmacodynamic parameters of a drug.
The slope of the linear regression from log percentage remaining vs. incubation time relationships (−kel) was used in the conversion to in vitro T1/2, values by in vitro T1/2 = 0.693/ kel.
