Conversely, modulation of hypoxia may provide benefit to patients with HNSCC [ 18], which underscores the importance of understanding the impact of therapies on tumor hypoxia and developing improved methods to modulate tumor pO2 and the molecular response to hypoxia.
Conversely, JMJD3 overexpression positively modulated the expression of the gene signatures of the myeloid development and mature hematopoietic cells (Fig. 4g and Supplementary Fig. 4f right panel).
Conversely, cytokine production is modulated by steroid and sex hormones [ 6, 7], and an increasing body of evidence suggests that oestrogen and progesterone participate in modulation of the secretion of proinflammatory and anti-inflammatory cytokines [ 7].
Conversely, 759 genes were modulated by P. viticola exclusively in T39-treated plants (cluster 10, ISR-responsive specific genes), and they represent the specific reaction to P. viticola of T39-treated plants.
Conversely, AtWRKY27 negatively modulates symptom development caused by Ralstonia solanacearum infection (Mukhtar et al. 2008).
Conversely, several NRs modulate the expression of calpains: retinoids, the ligands for retinoid acid receptors (RARs), estrogens, that mediates their action through the estrogen receptors (ERs) and the 1,25-dihydroxyvitamin D3, which uses the vitamin D receptor (VDR), have shown to regulate calpain activity [ 50- 54].
Conversely, circulating monocytes might be modulated by various factors, including cytokines, in the lead up to reach adipose tissue, resulting in the discrepancy of proinflammatory characteristics between monocytes and macrophages.
Thus, the effect of compounds was confined to cells, where excessive IL-6 production was deleterious; conversely, IL-6 was not modulated in peripheral blood leukocytes where it is required for an efficient humoral immune response.
Querying this database allows us to determine which TFs are modulated in a given experiment, or conversely, by which environmental conditions a given TF is modulated.
Conversely, clusters 2 and 6, consisting of genes modulated only during the pre-véraison interval, were the less populated ones.
