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The authors describe an interesting and quite extensive set of experiments showing that Golf supports AC5 protein expression, likely by increasing protein stability, and that AC5 has a converse effect on Golf abundance.
Importantly, the converse effect on P23H mobility was observed after ERdj5 overexpression, by prevention of the non-native C185 C187 disulphide bond or after short incubation with the reducing agent DTT.
Using the early committed progenitor gene sets, we found that the Cebpa KK mutation had the converse effect on HSC lineage programming compared with FOG-1 conditional knockout, leading to preGM gene depletion and preMegE gene enrichment.
Similar(57)
The converse effect of primaquine on chloroquine disposition was modest in comparison.
These changes in DNA charge had converse effects on the orientation preferences of heterodimers in which charged amino acid residues adjacent to the basic regions were exchanged between Fos and Jun.
Overexpression of MSI1 was sufficient to increase Hes1, stimulate proliferation, inhibit apoptosis and reduce insulin expression, whereas Msi1 knockdown had the converse effects on proliferation and insulin expression.
Our in vitro studies show that different therapeutic modalities may have converse effects on fascin expression and may have significant consequences for disease remission and the clinical management of IBD.
I'm greeted by Atomico's hard-working and always jovial head of communications, who seems slightly on edge, which I take as a compliment and has the converse effect of helping me relax.
We next tested the converse effect of suppressing SPRED2 using siRNA knockdown in PC3M cells.
This notion was further supported by the converse effect of the T3232A mutation, which enhanced Rad51 binding.
Although the impact of sex hormones on MS is well recognized, the converse effects of autoimmunity on sex hormones are still unclear.
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CEO of Professional Science Editing for Scientists @ prosciediting.com