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CITH was the starter of new developments as well as the coordinator of a complete strategy in medical area which associates fundamental research, preclinical evaluation and clinical applications with convergent orientations and sharing experience for a better evaluation of new ultrasound methods in medical area.
Because promoters are found in the TIRs, Mu internal sequences may be transcribed in convergent orientations (Hershberger et al. 1995; Lisch 2002).
In this RM system, the MTase and REase genes are convergent rather than divergent, though there are numerous examples of C-regulated RM systems with convergent orientations [ 9, 37].
The incidence of gene pairing can be as high as 24% in some species, and the gene pairs are found in all of the possible tandem, divergent, and convergent orientations.
We say that a ES pair is a valid pair (Raphael et al., 2003) if the ends have opposite, convergent orientations and the distance between the mapped ends is within the range of fragment lengths: i.e. (+ x C, − y C ) is valid if Lmin≤| y|−| x|≤ Lmax.
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CTCF sites at loop anchors occur predominantly (>90%) in a convergent orientation, with the asymmetric motifs "facing" one another.
A gene pair can be in tandem (++ or −−), divergent, or convergent orientation.
We provide initial evidences that bidirectional promoter and transcriptional read-through might in part explain antisense expression in genomic loci with tandem and convergent orientation, respectively.
(iv) In Arabidopsis, most of the cis-NATs are arranged in convergent orientation.
Only convergent orientation seems to permit some long overlaps, although convergent overlaps are also hampered by misannotations.
On the other hand, convergent orientation seems to allow longer overlaps than the other two orientations, although convergent long overlaps are also affected by misannotations.
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