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They also demonstrate that both CB1 and CB2 receptors display convergent effects, via complementary pathways [11], [13], [14].
Interestingly, although both receptors display convergent effects, pathways underlying CB1 effects are markedly different from those affected by CB2.
This might explain who TMS to the 2 sites may produce convergent effects.
Altogether, the three levels of activation produced convergent effects of OEA with the adrenergic mechanisms in the adipose tissue.
As suggested in some studies, a cluster of "harmful" interleukins exert synergistic and convergent effects on cardiovascular diseases and glucose metabolic alterations [ 30].
However, it is clear that obesity, metabolic syndrome, and type 2 diabetes are progressive, convergent effects of a chronic energy imbalance.
Similar(49)
Such results suggest that targeting cognitive bias may be a necessary and convergent effect of different treatments for depression.
The convergent effect of elevation on leaf economics could largely result from the fact that both evergreen and deciduous species tended to increase LMA and CC and decrease Wm, Amass, Rmass, Pmass and PNUE with increasing elevation.
In our experience, these different mechanisms act synergistically, and the generation of submicoscopic membrane phase transitions appears to be the convergent effect that precedes endocytosis (Hilgemann and Fine, 2011).
The reduced amount of cell‐surface expressed GABAARs in the presence of gephyrin‐G375D exerts a functionally convergent effect similar to that observed by mutations of genes encoding core components of GABAergic postsynapses, for example, GABAAR subunits and collybistin.
Our findings further support the notion that the selection of the predicted microRNA targets relies on the rank (strength) of the target prediction scores (Table S1) and that the functional regulation relies on the level of microRNA expression in the cell and convergent, synergistic effects of multiple microRNAs on one target gene.
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