The bi-molecular nature of the DOCK1/ELMO Rac-GEF argues that, in contrast to conventional Rac-GEFs in which the DH and PH domains act as cis-acting elements, a significant aspect of the regulation of DOCK/ELMO mediated catalysis depends on the regulation of the association between DOCK1 and ELMO proteins, as well as other trans-acting factors.
Of interest to us was the non-conventional Rac-GEF, SWAP70 [ 14].
The relationship between recycled aggregates concrete (RAC) and conventional concrete (RC) is expressed by fundamental parameters α, which describe the relevant equivalent properties of RAC in function of the same property of RC.
This test considers 36 specimens of recycled aggregate concrete (RAC) and conventional concrete.
Compared to conventional concrete, the frequency of RAC with 100% RCA reduced by 11% and its damping ratio increased by 17%.
Conventional GEFs bind nucleotide-free Rac via their DH domain, while the CDM proteins use the DHR2 region.
The mechanical properties of recycled aggregate concrete (RAC) were compared with conventional concrete with SP, and found that the compressive strength of RAC was ~90 % that of conventional concrete.
Our finding on the stress-induced rapid Rac activation challenges the conventional wisdom on mechanotransduction and suggests that stress-induced signaling does not follow signal transduction pathways induced by growth factors.
Split tensile strength and modulus of elasticity in RAC was comparable in both the conventional as well as PPM methods.
This study investigated mechanical properties of RAC by using new methodology and conventional methodology at different replacement percentages of RA.
The test results show that the damping ratio of RAC was higher than that of conventional concrete when the compressive strength was similar, while the vibration frequency of RAC was lower than that of conventional concrete.
