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As typical eukaryotic organisms, fungal cells use conventional pathways of secretion involving post-Golgi vesicles that fuse with the plasma membrane to release their cargo [5], [6].
In the inflamed synovial joint, persistence is probably mediated more through over-exuberant co-stimulatory pathways in T cells than through conventional pathways of antigen-specific activation.
Conversely, the conventional pathways of biochemistry that should form the core of a functionally oriented partitioning are typically linear or circular and only weakly connected in terms of graph structure.
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Fig. 5 The conventional pathway of the DHA under three culture modes.
The conventional pathway of DHA synthesis (Vaezi et al. 2013) has two routes from linoleic acid (LA, C18 2) to DHA by a consecutive series of desaturation and elongation steps as shown in Fig. 5.
Complementary to our initial microarray comparisons of sporadic polyps from the serrated and conventional pathway of colorectal carcinogenesis, somatic RNF43 mutations appeared mutually exclusive with deleterious APC mutations.
In the conventional pathway, biosynthesis of LC-PUFAs starts with the Δ6-desaturation of LA (n-6) and ALA (n-3), generating γ-linolenic acid (GLA, 18 3 Δ6,9,12) and stearidonic acid (SDA, 18 4 Δ6,9,12,15), respectively.
Therefore, the comparison is limited to conventional pathways, and different parts of the cellular metabolism are not associated with each other.
However, no definite uptake of aSNPs via such conventional pathways could be detected (data not shown).
The prevalence of manipulation was lower or comparable to that in most published studies following more conventional pathways.
8 20 21 Experimental data to date on the role of NO in modulating IOP through the conventional pathway were the focus of a recent review.
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