Sentence examples for conventional conjugation from inspiring English sources

It is becoming increasingly clear that site-specific conjugation offers significant advantages over conventional conjugation chemistries used to make antibody drug conjugates (ADCs).

This synthetic approach uniquely allows for the direct fabrication of biologically functionalized gel scaffolds with ideal structures for adipose tissue engineering, which provides a competitive alternative to conventional conjugation techniques such as copper mediated click chemistry.

Antibodies are also difficult to be manipulated for drug conjugation via the conventional conjugation and linker chemistries, as they are too big to be synthesized chemically and too complex to be produced in microorganisms.

Conventional conjugation methods generally work well with antibodies (Wilson and Nakane 1978); however, results with many antigens of less well-established structures are less constant (Hermanson 2008; Ge et al. 2012).

The three alternatives to conventional conjugation techniques include conjugation via novel unpaired cysteine residues conjugation via transglutaminases and, finally, conjugation via unnatural amino acids.

However, to effectively immobilize GLP-1 within hydrogels without compromising its bioactivity remains challenging with conventional conjugation schemes that involve reactions with primary amines.

Conventional antibody conjugation methods generate antibody-drug conjugates that are heterogeneous mixtures with undefined stoichiometry and variable pharmacokinetic and pharmacodynamic properties.

To circumvent the effect on antigenic structure caused by conventional chemical conjugation that could result in decrease in sensitivity of DS-ELISAs, a novel HRP-conjugated antigen (Cap∆41) was constructed by affinity binding (Fig. 1) and utilized to establish a new double-antigen sandwich ELISA for PCV2 antibody detection.

The results show a potential for p18-4 decorated liposomes prepared by conventional and post conjugation method for tumor targeted delivery of DOX in breast tumor models.

The conventional and post conjugation methods of peptide incorporation were found to be more reliable for the preparation of p18-4 decorated liposomes for active DOX targeting to MDA-MB-435 cells.

As previously mentioned, the conventional two-step conjugation method was designed to minimize affecting the second protein's carboxyls.