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Despite the controversies above, the question that remains germane is whether molecular profiling offers more than the information provided by clinicopatho-logical parameters and a handful of immunohisto-chemical markers.
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The controversies cited above prompted us to evaluate whether the histone γ-H2AX test is able to predict the clinical RT outcome of RC patients and to discriminate them from healthy subjects.
This has led to the dating controversy mentioned above, and to other candidates for the famous face.
This is the main significance of the controversy discussed above over Henrich et al.'s interpretation of their field data.
The aim of the current study was to resolve the cross-modal AB controversy described above by taking an individual differences approach combined with the use of equivalent independent targets that differed only in modality.
The controversy described above is even bigger for another type of IgE effector cells in and around tumors, mast cells (129).
Further studies are required to confirm whether the controversy presented above comes from differences in the species of experimental animals used and/or differences in the pharmacological properties of each δ receptor agonist and antagonist used.
The discussion of media coverage of scientific controversy above gave a few examples of secondary scientific controversies in evolutionary biology.
The section on scientific controversy above briefly describes secondary scientific controversies about human evolution and controversies over the application of evolutionary research to conservation.
Despite the above controversies, consensus guidelines from European groups [63,64], Canada [65] and the United States of America [66] recommend preoperative chemoradiation for the majority of patients with stage II and stage III rectal cancer.
In view of the above controversies on mechanisms and predictive values, we evaluated and compared filling volumes to pressures in determining the cardiac response to fluid loading according to systolic cardiac function in sepsis-induced hypotension, in the hypothesis that, even in dysfunctioning hearts, cardiac dilatation is required to increase cardiac output upon fluid loading.
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CEO of Professional Science Editing for Scientists @ prosciediting.com