NGS has also resulted in the correction of some previously-controversial linkages of susceptibility genes with diseases.
However, the nature of the sex-linkage is controversial, with evidence for both X- and Y-linkage of the 2D:4D phenotype.
However, the absolute requirement for the formation of K11-polyUb linkages is controversial, as multiple monoubiquitin (monoUb) linkages are sufficient for mitotic progression (Dimova et al., 2012), and chains formed by the APC/C contain heterotypic branched K48 and K11 linkages, rather than homotypic K11 chains (Meyer and Rape, 2014).
When they do trickle down to controversial projects, the NEA linkage alone is usually enough to lubricate a manufactured outrage – such as when the Christian Action Network made a huff about an NEA grant to HIV-positive performartistRon Athey Athey, who received a measly $100 stipend from a $100,000 purse given to the Walker Art Centre in Minneapolis.
For example use of SNPs (diallelic markers) for linkage is still controversial, especially for extended pedigrees, because statistical software to analyze this data is still not really available.
The linkage used to be controversial (maybe aggressive people watch more TV than others), but we now see that it's an issue of our deferred-imitation abilities, coupled with a loss of impulse control.
The controversial location in the literature is the linkage of cylinder and dome of containment building.
A week ago, I revealed that Poizner was going up on the air with a rugged TV ad attacking Whitman, a controversial former Goldman Sachs board member, for her deep linkages to the investment banking house.
A gene shown to be associated with many cases of schizophrenia or manic depression might also reduce stigma, aid in diagnosis, or be used as a screening tool, an application bound to be controversial, said Dr. Kendler, who with colleagues has reported linkage findings for schizophrenia on Chromosomes 5, 6, 8 and 10.
This linkage between poetry and rhetoric is of course controversial, and will be discussed below.
Case-control studies on candidate genes may have greater power compared to linkage analysis, but the results have been largely controversial [64].
