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Using a mouse model of infection with virulent Mycobacterium tuberculosis (Mtb), we identified the genetic locus sst1 that controls the progression of pulmonary tuberculosis in immunocompetent hosts.
The cell's redox status controls the progression of the cell cycle, including misregulation in cancer [1], [2].
We showed previously that lysophosphatidic acid (LPA) produced in the tumor microenvironment controls the progression of osteolytic bone metastases of breast cancer cells and highlighted the important role of blood platelets in this process [4].
For example, miR-221/222 were found to down-regulate p27Kip1/CDKN1B and the c-KIT receptor, which controls the progression of neoplasia leading to enhanced proliferation and reduced differentiation in melanoma cells [42].
Similarly, phosphorylation of histone-3, which controls the progression of mitosis, was strongly reduced after 24 h treatment.
On the other hand, the extract effectively controls the progression of 4T1 in LR mice by its antiproliferation, antiinflammation and immunomodulation effects.
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Our study showed that HDAC inhibition attenuates progressive dysfunction, suggesting that HDACs play an important role in controlling the progression of heart failure.
Our findings strongly suggest that targeting EVPs is a valid strategy in controlling the progression and spread of cancer.
The MIDI messages were used to control the progression of a computer-generated accompaniement and a visual part.
In chronically epileptic mice, real-time optogenetic modulation of MCs during spontaneous hippocampal seizures controlled the progression of activity from an electrographic to convulsive seizure.
Ultimately, these models could be useful to guide the design of novel therapies, which allow us to control the progression of heart failure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com