Sentence examples for controls phosphorylation of from inspiring English sources
The PI3K/mTOR signaling pathway controls phosphorylation of 4E-BP1 and S6K, and S6K1 also phosphorylates S6, and has been proposed to phosphorylate EF2K and pdcd4, controlling the activity of S6 and EF2K, and protein stability of pdcd4 [ 20, 30- 32].
Furthermore, it was shown that Rad17 ubiquitylation controls phosphorylation of Rad53, the yeast Chk2 orthologue, a downstream component of the DNA damage response [27].
A key question concerns the mechanism by which LRRK2 controls phosphorylation of Ser and Ser.
The key finding of the present study is that the kinase activity of LRRK2 indirectly controls phosphorylation of Ser/Ser and hence 14-3-3 14-3-3 14-3-3ell as LRRK2 cytoplasmic localization.
Compared to controls, phosphorylation of AMPK and its downstream signaling molecule Akt increased in the aortic tissue of the sitagliptin group(p < 0.05 and p < 0.01), while the phosphorylation of p38 and ERK1/2 decreased (p < 0.05 and p < 0.01).
The Rho/ROCK signaling pathway controls phosphorylation of the myosin light chain and mediates the enhanced acto-myosin contractility that is a critical feature of amoeboid cells [ 10, 11, 14].
Hyperphosphorylation of CKIε's C-terminus thus inhibits the binding of substrate proteins, and may act as a regulatory mechanism to control phosphorylation of targets.
The bacterial chemotaxis, which is mediated by two-component systems, directs motile cells to favourable environments by controlling phosphorylation of histidine kinase CheA and its cognate response regulator CheY.
Several of these changes affect the kinase cascades that control phosphorylation of Myc.
ERG has previously been reported to control phosphorylation of GSK3β (Ser9) by regulating the WNT pathway [ 8].
