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Individuals with any known malignancy were excluded from the controls of the study.
Table 2 summarizes information on demographics, smoking history, and environmental smoking exposure in the cases and controls of the study sample, after excluding 157 cases and 4 controls without a complete baseline questionnaire.
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The man in control of the study is Dr. Andrew Conrad of Google X, but Google is not conducting the experiment alone: Duke University and Stanford University medical schools are working closely with the search giant to design the experiments and study the data.
Pfizer's sponsorship of the trial inevitably raises the question of potential bias, but the researchers, from the respected Cleveland Clinic, say they had complete control of the study, data analysis and preparation of a scientific paper.
Kastelein says if he had been in full control of the study, results would have been presented last March.
On 24 July, a California superior court found in favor of UCSD, issuing a preliminary injunction to restore control of the study data to the school.
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Since 3 of the 5 cases were in households where reinfestation could not have occurred it appears the risk of reinfestation from outside the family, and the control of the study, may be greater than between siblings.
Final multivariable analyses were conducted using STATA to ensure control of the study design effects, proper analysis of the five imputed datasets and correct estimates of standard errors [29], [30], [31].
This limitation is beyond the control of the study.
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