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The negative controls of breast tissue showed no staining.
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A separate search identified five randomized controlled trials (RCTs) with a wait-list control of breast cancer patients receiving standard care that reported data on fatigue.
17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) enzyme catalyses the synthesis of the active female estrogen, estradiol and is thus an attractive target for structure-based ligand design for the prevention and control of breast tumour growth.
Importantly, the cytotoxic effect of 2l was 10 15-fold 10 15-foldcancer thighern-cancer cells, suggesting that this conpound cancer very effecthan for the control of breast cancer with low side effecells
The breast cancer network model we present in this work integrates the current knowledge of PIK3CA-mutant, ER+ breast cancers, and uses it to identify a set of elements that may eventually be exploited in high-order therapeutic combinations to achieve a more durable control of breast cancer.
Brachytherapy has demonstrated excellent local control of breast cancer at follow-up of up to 6 years post treatment.
Our data, thus, raises the possibility that Akt2 can be an effective anticancer target for the control of (breast) cancer.
Therefore, delineating how negative growth control of breast epithelial cells is lost during tumor formation is essential to understand the pathogenesis of breast cancer.
This study was initiated on the basis of previous findings from our group that showed a role of Erk5 in the control of breast cancer cell proliferation [14].
Our results, in terms of its overexpression and inhibition, demonstrate that ACSL4 plays a causal role in the control of breast cancer aggressiveness.
However, independently of which mechanism takes place, it was recently shown that reduction or absence of KLF6 abrogates the negative control of breast cancer cell proliferation triggered by Estrogen Receptor alpha through the signaling pathway mediated by c-Src and Akt activation [49].
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