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Initially, the allele frequency for each individual SNP was determined for all the cases and all the controls in pools of DNA.
rs11084424, rs157580 and rs157581 showed allele frequency differences between cases and controls in pools of 4%, 9% and 17% respectively which compared well with the real differences of 3%, 10%and19%9%and19%
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For RNA purification, leaves (the second and third leaf) and roots from control or treated plants were collected separately in pools of 6 plants after 3 (14 00 pm) and 24 h (11 00 am) of PEG treatment.
The hypotheses that these SNPs are associated with MI were tested in Study 3. We determined the allele frequency of each SNP in pools of case and control DNA prior to determining the genotype of a smaller number of SNPs for all individual DNA samples.
Mosquito control boards try to eliminate as many mosquitoes as possible when they are larvae, swimming in pools of water.
Assuming 144 candidate external RNA controls, the pre-labeled targets will be split into three pools (e.g., controls 1 48 in pool 1, controls 49 96 in pool 2 and controls 97 144 in pool 3) and a fourth pool of all pre-labeled transcripts will be generated.
In order to determine the potential of each probe sequence to detect different levels of methylation from the selected CpG sites, we hybridized control pools of in-vitro methylated as well as unmethylated PCR fragments to individual microarrays.
Expression of either EWS/WT1 isoform increased proliferation rates compared to eGFP controls in multiple, independent pools of SV40 large T antigen transformed MEFs (p value <0.05) but not E1A/RAS transformed MEFs.
Top managers in the private equity business may be in control of vast pools of funding and more and more voting rights, but they have not been in control of their own images.
By controlling the pools of PAP and PAPS in the cell, Rv2131c is poised to serve as a key regulator of the sulfate assimilation pathway.
Consistent with a role for the HARBS PDE4 conformer in controlling the pool of cAMP that activates Epac to elicit neurite outgrowth, we noted that both R-rolipram and RS25344 significantly promoted neurite extension across the lesion, while the LARBS selective PDE4 inhibitor, S-rolipram, was ineffective.
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