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For example, Gaïni and colleagues [ 95] reported that circulating HMGB1 levels are increased (relative to healthy controls) in intensive care unit (ICU) patients with infections, sepsis, or severe sepsis (that is, sepsis with organ dysfunction).
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Thus, further studies on this subject will be recommended to define the exact place of glycemic control in intensive care.
Achieving good glycemic control in intensive care units (ICU) requires a safe and efficient insulin infusion protocol (IIP).
Professionals' views on various aspects of glycaemic control in intensive care were associated with their profession and level of experience.
Numerous guidelines have been developed and tested to implement tight glycaemic control in intensive care units.
Although glycaemic control in intensive care patients has been fertile ground for research over many years, optimizing cerebral glucose in acute brain injury has more recently attracted the interest of physicians involved in neurocritical care.
Tight glycemic control in intensive care, however, did not reduce mortality or morbidity in a meta-analysis of 27 studies, while being associated with increased likelihood of hypoglycemia (29).
But this is true only up to a point since in these days of insulin infusion algorithms aimed at achieving excellent glycemic control in intensive care situations and the use of premeal corrective insulin doses in patients using multiple dose insulin regimens, the differences mentioned could quite conceivably compromise the success of those respective treatment strategies.
*Data missing for success (4 control and 1 intervention); compliance (1 control in intensive phase, 13 control and 14 intervention in continuation phase); weight (11 control and 16 intervention at 8 weeks, 42 control and 40 intervention at 32 weeks); cough (3 control and 14 intervention at 4 weeks, 35 control and 38 intervention at 8 weeks, 38 control and 42 intervention at 32 weeks).
This review investigated whether the administration of enteral pre-, pro- and synbiotics compared with controls in adult intensive care unit (ICU) patients reduced the incidence of nosocomial infections, length of ICU stay, hospital mortality and specifically pneumonia.
The participation of nurses is of extraordinary importance for the success of infection control programs in intensive care [ 25, 26 ].
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