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We also tabulated percent density against various breast cancer risk factors within the controls (data available from the authors).
Hydralazine, H2O2, and ONOO− all increased KIR expression on the CD4+CD28+ and CD4+CD28− subsets (P < 0.05 for all 3 treatments versus untreated controls) (data available from the author upon request).
We obtained global DNA methylation data for 42 melanoma patients and 46 controls as well as for 86 breast cancer patients and 92 controls (data available in Additional files 3 and 4).
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We do not have direct control data available on this issue, but we believe on review of the presented data that this assertion is flawed.
Use-case 1: Quality controlled data available through EMODnet As mentioned earlier, the results of the assigned quality control flags can be combined according to the required 'fitness for use' for the users, thereby generating the possibility to create specific filters on the available data within EurOBIS and OBIS.
There were 278 female cases and 358 female controls with data available for analysis.
There were 545 SLE patients and 386 controls with data available for analysis (Table 1).
It is interesting to note that conflicting messages about treatment were not reported in the study by Allen et al. in the field of early stage breast cancer, likely reflecting the wealth of high quality randomized controlled trial data available in that field.
An RCT or an observational study was included if it met the following criteria: adult patients experienced infection or sepsis, statins compared with a control and data available on the mortality.
Whilst skin fibroblasts were propagated for enzyme analysis it was clear that those from the subject harboring the mutation had a reduced doubling time on glucose medium compared to control lines (data available on request).
For all variants with case-control genotype data available in three or more independent samples, we calculated crude ORs (Odds Ratios) and 95% C.I. values of the addiction susceptibility from the allelic distributions for each study following the published protocols [ 4].
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