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Based on visual inspection of grand averaged waveforms (see Figure 1), MMN amplitude and latency was obtained for each group (Controls, At risk) and condition (Standard, Deviant) over 12 frontocentral electrode sites (FP1, FPz, FP2, F1, Fz, F2, FC1, FCz, FC2, C3, Cz, C4).
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The same analysis was repeated based on diagnostic classification of infants at 36-months (control, at-risk ASD, at-risk typical, at-risk other).
Testing the relationship between infant brain function measures and later outcomes followed on from the previous analysis based on risk groups but involved splitting the at-risk group based on their outcomes (control, at-risk ASD, at-risk no ASD).
A model was constructed with the following terms: between subjects groups (control, at-risk), and within-participants time (7-months vs. 14-months) and trial segment (first 5 s vs. last 10 s).
Neither the risk groups (at-risk, control) nor groups defined based on 36-month outcomes (control, at-risk-ASD, at-risk-typical, at-risk-other) differed in the total number of trials completed or in the number of valid trials (all ps>.12) or in the percentage of trials where they failed to disengage (all ps>.15).
To test our hypothesis, we used a generalized linear model (GLM) with the following repeated measures factors: condition (baseline, overlap), age (7 months, 14 months), and outcome group ascertained at 36 months (control, at-risk-typical, at-risk-other, at-risk-ASD) as a between-subjects factor.
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The Virginia House just passed a bill that would require women seeking abortions to undergo an invasive trans-vaginal ultrasound without their consent, and another that would put access to birth control at risk.
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aLower FVC in PAH and ILD groups, versus "at risk" and controls bLower DLCO in PAH and ILD groups, versus "at risk" and controls.
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