Suggestions(2)
Exact(11)
To evaluate the potential of a particular protease as a drug target, use of a reagent that controls activity of the protease is indispensable.
It seems unlikely that this pathway controls activity of constitutive membrane recycling machinery such as Rab5 [38] but could act by coupling between E-cadh and this machinery.
Among these is the regulation of VH germline transcripts as so far no cis-regulatory element has been identified that controls activity of the bulk of unrearranged VH promoters.
Phosphorylation controls activity of these proteins [ 9, 10].
TIMP-1 controls activity of most MMPs, whereas TIMP-2 specifically inhibits MMP-2.
PAK1 regulates the activity of an unknown MAP kinase kinase kinase, which controls activity of MKK4.
Similar(49)
Upstream, the subgroup of BH3-only proteins controls activities of pro- and anti-apoptotic Bcl2 family members.
Sustained activation of NMDA receptors (NMDARs) plays an important role in controlling activity of neural circuits in the brain.
The activity of uninhibited urease was accounted as the control activity of 100%.
Previous studies [21, 22] showed that MSC control activity of pulmonary VEC through regulating microRNAs (miRNAs) levels.
These antibiotics are further distinguished by their novel mechanism of action in which they bind and deregulate the tightly controlled activity of the cytoplasmic protease ClpP.
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Justyna Jupowicz-Kozak
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