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However, only slow intracellular mechanisms have so far been described for controlling their localization as real-time visualization of endogenous voltage-gated channels at high temporal and spatial resolution has not been achieved yet.
Also called nuclear-enriched abundant transcript 2, MALAT1 localizes to nuclear speckles where it regulates the phosphorylation of the pre-mRNA splicing factors such as SR proteins, thereby controlling their localization and activity [ 93, 94].
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CPEB proteins function to bind mRNAs in order to control their localization and subsequent translation.
Future analyses of how S-palmitoylation of additional immune receptors controls their localization, interactions and signaling will be an exciting area of future study, as will the examination of potential subversion of TLR2 S-palmitoylation by pathogens.
PKA also directly regulates Msn2,4 by controlling their nuclear localization (Gorner et al., 1998).
Cross-linked albumin film, which has unique surface properties capable of regulating protein adsorption, was used to control their spatial localization.
The family consists of six IGFBPs (1 6) that bind insulin growth factors (IGFs) with high affinity (dissociation constant [KD] 0.1 nM) to control their transport, localization, and metabolic breakdown [4].
Although small molecule sensors are still the most commonly used imaging probes, it has proven challenging to control their subcellular localization and concentration.
The post-translational addition of palmitate or palmitoic acid to Wnts renders them highly hydrophobic and is believed to control their secretion and membrane localization [ 4, 9, 10].
It is therefore necessary to understand the electronic structure beyond the formal oxidation state and how PS II manages electron localization and controls their paths using the flexible protein environment; this may be an important aspect for learning the design concept of the catalytic reaction and applying it to artificial photosynthetic devices.
Expression of S1PR by blood cancer cells may directly regulate their survival by controlling the localization of cells within permissive environments such as the lymph nodes (Blaho & Hla, 2014).
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