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Combing this network regularizer R with the objective function in Eq. (8), we obtain the objective function of RNMF as follows (11) O = | | X - U V T | | 2 + α | | W ⊙ (Y - B V T ) | | 2 + β Tr (V T L V ) where β is the regularization parameter controlling the importance of the network regularization term.
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Parameter ƞ controls the importance of two kinds of seed nodes, i.e. drug node and target node.
This is balanced by the weighting factor ηC in (22) which controls the importance of the geometric constraint relative to the separation criterion.
where the weighting parameter ηC can be chosen to control the importance of the geometric constraint relative to the separation criterion represented by JBSS (3).
where ( tilde{t} ) is the transmission map to be refined and a weight λ controls the importance of the data term.
S (v ) = w (v ) + λ ∑ u ∈ V w (u, v ) Where S (v ) is the score of node v, λ controls the importance of the edge weight relative to the node weight.
The top two sliders control the importance of terms matching to GO and PO, respectively; the bottom slider in this column controls the weight for query terms that did not match an ontology.
Finally, α ∈ 0[ 1] is a parameter controlling the relative importance of the phenotype vs. the PCC value.
The Lagrange multiplier λ in Equations (3) and (4) controls the relative importance of rate versus distortion in the total cost.
The parameters θ fully control the relative importance of the reproducing the observational data to honoring the continuity of the physical properties, and so these parameters are often referred to as hyperparameters.
The parameter α in PR controls the relative importance of prior information.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com