Sentence examples for controlling the apoptotic from inspiring English sources

In diet-induced inflammation of the hypothalamus, TLR4 exerts a dual function, on one side activating pro-inflammatory pathways that play a central role in the development of resistance to leptin and insulin, and on the other side restraining further damage by controlling the apoptotic activity.

Thus, it is likely that, in diet-induced inflammation of the hypothalamus, TLR4 exerts a dual function, on one side activating pro-inflammatory pathways that play a central role in the development of resistance to leptin and insulin, and on the other side restraining further damage by controlling the apoptotic activity.

Nonetheless, the pathway controlling the apoptotic process may depend on the activation state of the cell.

Our results show that the protective effects of S. crispus ethanolic extracts are mediated, at least in part, by controlling the apoptotic pathway [ 39].

The absence of apoptosis in Ncadk.i. p53 MG indicates that p53 acts downstream of p-Stat3 signaling and is central in controlling the apoptotic process in involution.

To evaluate if Sp-1/miR-29b loop has a role in controlling the apoptotic process in MM cells, we investigated the contribution of miR-29b in the response of MM cells to bortezomib.

Clarifying how the Bcl-2 family governs apoptosis might provide the ability to control the apoptotic threshold.

bcl-2 is one of a family of genes that control the apoptotic threshold of a cell.

There are also genes which are inherently different between the two lines studied, including many genes, which control the apoptotic potential of the host.

A critical step controlling the TG2-dependent apoptotic pathway is nuclear localization of TG2.

Independently of its transcription-regulatory mechanism p53 can also directly interact with proteins of Bcl2 family controlling the execution of apoptotic response [ 4].