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This study points to the importance of controlling for possible changes in socio-demographic distributions when different cohorts are compared.
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MacLeod conducted his analysis approximately 4,500 km (2,800 mi) from the Chicxulub Crater to control for possible changes in soil composition at the impact site, while still close enough to be affected by the impact.
For randomization within each stratum, the method of random permuted blocks is used to control for possible changes over time in the subject mix.
Permuted block randomization with each stratum (IHSP versus other recruitment source) to control for possible changes over time in subject mix was employed.
Finally, the regression model is more or less unaltered when we include a calendar year variable to control for possible changes over time, such as external shocks to economy (model 18).
This would limit the inferences that could be drawn from the equivalence analysis carried out, as we could not control for possible changes in health between completions that could differ depending on differences in the time taken to complete both study arms.
In addition, a third group of mice were immunized with OVA-conjugated pure liposomes prepared with the same lipid composition as the LCMPs to control for possible changes in the lipid structure or composition occurring during budding of vesicles from the PLGA-core particles.
Within the statistical analysis, we will control for possible changes in anti-dementia drug treatment in both groups.
Given that changes in the actual size of red blood cells can affect the packed cell volume of Hct, Hgb is used in the PV equation to control for possible changes in mean corpuscular volume [ 22].
2) How does the effect of these SES indicators change after controlling for possible confounders?
Multivariate regression models will be developed to compare changes in the primary and secondary outcome measures between the intervention and control groups while clustering by physician and controlling for possible confounders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com