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Variation of the concentration of α-ketoglutarate through its physiological range provided dramatic regulation of the ability of PII to activate the phosphatase activity of NRII and controlled the ability of PII to inhibit the autophosphorylation of NRII.
2 If so, this could aid decisions on the use of a combination of biological disease-modifying antirheumatic drugs (DMARD) and conventional synthetic (cs)DMARDs versus step-up therapy in early RA. 3 Once RA is well controlled, the ability to sustain remission following the withdrawal of immunomodulatory medications would be an indication of disease modification.
However, persistence of antimicrobial resistance within vaccine and nonvaccine serotypes (37– 40) suggests that vaccine alone may not reduce antimicrobial resistance, and that if the use of antimicrobial drugs is not controlled, the ability of the pneumococcal conjugate vaccine to reduce antimicrobial-resistant S. pneumoniae may be only transient.
The simplest explanation for the data shown here is that α-ketoglutarate did not affect the binding of PII to NRII but controlled the ability of PII to activate the NRII-regulated phosphatase activity or inhibit NRII autophosphorylation once PII was bound to NRII.
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It leads to self-control, the ability to formulate strategies in order to resist impulses.
In addition, the node permission is employed to control the ability to request files.
"The critical population size, which controls the ability of the tumor to adapt, depends on evolutionary parameters of the cancer," Gore and colleagues argue.
The Milwaukee Journal Sentinal wrote of "the broad-band war, the struggle over who will control the ability to deliver seamless streams of data to consumers".
The size of that opening controls the ability to get those blurry backgrounds that make portraits flattering.
Thus, the nervous system controls levels of fast Synaptotagmin isoforms to regulate release kinetics and thereby controls the ability of synapses to encode spike rates or precise timing.
Mitchell Lazar and colleagues discovered a critical and novel role of the epigenetic modulator HDAC3 in controlling the ability of BAT to respond to acute thermogenic challenges.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com