To control for the plausibility of the results, the three-path mediation models were re-calculated with an inverted sequence of mediators.
Data are entered via special MS Access entry masks automatically controlling for data plausibility.
Data were entered via special MS Access entry masks automatically controlling for data plausibility.
All analyses were controlled for total energy intake, plausibility of energy reporting, alcohol intake level, smoking status, educational attainment, recreational physical activity index, and menopausal status, in women.
Therefore, data controls for plausibility were performed to identify and correct data input errors (e.g. for quantities, extremes in energy and nutrient intake) and about 3400 interviewer's comments were checked and integrated into the interview data.
As a control for plausibility the copy number of mRNA for the low-abundance housekeeping gene TBP (TATA-box binding protein) was also determined and was expected to be between 20 and 40 copies per normal resting cell (data not shown).
All analyses were, therefore, controlled and tested for plausibility.
A prespecified validation plan was used to check for plausibility.
With strong and consistent effects shown in epidemiologic studies and controlled exposures, biologic plausibility for inflammatory effects, and appropriate temporal relationships, the evidence is close to documenting a causal relationship between endotoxin and exacerbation in asthmatics.
There might be other reasons for this perhaps workers in higher-level positions have offices with nicer views and have greater job satisfaction, regardless of stress levels but the results held even after controlling for worker age [a proxy for greater responsibility] reducing the plausibility of this explanation.
